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Molecular Mechanisms of
Muscle Atrophy & Cancer Cachexia

Monday, February 6, 2017
3:30-5:00 PM
(Coffee and snacks provided)
Functions of the Proteasome – From Protein Degradation to Drug Development
Tuesday, February 7, 2017
10:00-11:30 AM
(Coffee and snacks provided)

Gross Hall; Thorpe Conference Center
845 Health Science Rd
Irvine CA 92697


RSVP to Diana Vigil; dvigil1@uci.edu

Dr. Goldberg’s major discoveries have concerned the biochemical mechanisms and physiological regulation of protein breakdown in cells and the importance of this process in human disease. His laboratory first discovered the ATP-dependent system for protein breakdown, now termed the ubiquitin-proteasome pathway. Dr. Goldberg’s lab first introduced the proteasome inhibitors now widely used as research tools, and he initiated the research effort that led to the development of the inhibitor, Bortezomib/Velcade®, now widely used in the treatment of certain cancers. He has published over 400 scientific papers and is among the one percent most-cited authors in the life sciences. Dr. Goldberg has been on the faculty of Harvard Medical School his entire career. He received his AB degree in 1963 and his Ph.D. in Physiology from Harvard University after attending Harvard Medical School and Cambridge University.

Dr. Goldberg’s accomplishments have been recognized with many distinguished prizes, including the Novartis-Drew Award, Severo Ochoa Award (New York University), Knobil Prize for Medical Research (Univ Texas, the Gabbay Award for Biotechnology and Medicine (Brandeis University), Norman Alpert Prize for Medical Research (Harvard), and Ernest Beutler Prize for Basic Research (Amer Hematology Soc.). He is a fellow of the American Academy of Arts & Sciences and a member of the National Academy of Sciences and the National Institute of Medicine. He has received honorary degrees from Cold Spring Harbor Laboratories, the Univ of Maastricht (Netherlands) and Univ. of Barcelona (Spain) and is among the 1% most cited authors in the life sciences.

Sponsored by: ICTS, UCI Exercise Medicine Sports Science Initiative & Department of Physiology and Biophysics