Have trouble viewing this email? Click here



The UC Irvine Institute for Clinical and Translational Science (ICTS) proudly announces a new call for the NIH/NCATS Mentored Career award (KL-2) under the UCI Clinical and Translational Science Award (CTSA/ICTS). The ICTS-KL-2 award is intended to support a two-year period of mentored career development. It is expected that during this time, the scholars will develop a solid portfolio of pilot and preliminary data suitable for competitive extramural grant applications; a robust record of publications and presentations at national scientific meetings; and a program of courses and experiential learning in areas that will advance the scholar’s proficiency in independent translational research. Scholars must demonstrate a productive relationship with qualified and funded mentors who are experienced in advancing the careers of translational researchers.


Scholar Candidates
Scholars supported under the KL2 component must have a research or health-professional doctoral degree or its equivalent.

Scholar appointments
Candidates must have a full-time appointment at UCI.

Selection restrictions
At the time of their appointments, scholars must not have pending an application for any other PHS mentored career development award (e.g. K07, K08, K22, K23) that duplicates any of the provisions of the K component. Former or current PDs/PIs on any NIH research project grant [this does not include NIH small grants (R03), exploratory Developmental (R21) or SBIR, STTR (R43, R44 grants)] or equivalent non-PHS peer reviewed grants that are over $100,000 direct costs per year, or project leaders on sub-projects of program project (P01) or center grants (P50) are NOT eligible to participate as scholars. Appointed scholars are encouraged to apply for individual mentored K awards (e.g. K07, K08, K22, K23) and independent awards (R01, R03, R21); if successful, the KL2 appointment would be terminated and funding received from the new individual K or R award. Scholars to be supported by the institutional career development program must be at the career level for which the planned program is intended.  In keeping with the type of mentoring and career development being provided by the CTSA, a KL2 scholar candidate who is already in the process of applying for an independent mentored career development grant, a P01 grant, or R01 grant is likely too senior for the KL2 award.

The ICTS annually funds three KL-2 scholars. A minimum of 75% effort must be dedicated to pursuing multidisciplinary clinical research and translational science including training and mentoring for a minimum of 2 years. During the 2 years of ICTS support, ICTS will work with the scholar through dedicated mentoring and monitoring to apply for an individual NIH K-award. The faculty scholar's home department, School, or organized research unit is expected to contribute the balance of the scholar's salary and research support during the period covered by the award.

For complete details of program including total award, eligibility, requirements click Here

Application Process

  • Full applications are due by 5pm on Wednesday September 23, 2015.
  • The final application includes:
    • Scholar Information. (4 Pages) Please address:
      • Summary of the degree to which the application meets five ICTS-KL-2 scholar selection criteria
        • Format.  Substantial face-to-face discussions among the career recipient/scholars, other individuals in a similar training status, and mentors along with a combination of didactic and small-group discussions (e.g. case studies) are highly encouraged.
        • Subject Matter. While there are no specific curricular requirements for instruction in responsible conduct of research, the following topics have been incorporated into most acceptable plans for such instruction:
          • conflict of interest – personal, professional, and financial
          • policies regarding human subjects, live vertebrate animal subjects in research, and safe laboratory practices
          • mentor/mentee responsibilities and relationships
          • collaborative research including collaborations with industry
          • peer review
          • data acquisition and laboratory tools; management, sharing and ownership
          • research misconduct and policies for handling misconduct
          • responsible authorship and publication
          • the scientist as a responsible member of society, contemporary ethical issues in biomedical research, and the environmental and societal impacts of scientific research
        • Faculty Participation. Mentors and other appropriate faculty are highly encouraged to contribute both to formal and informal instruction in responsible conduct of research. Informal instruction occurs in the course of laboratory interactions and in other informal situations throughout the year.
        • Duration of Instruction. Instruction should involve substantive contact hours between the career recipient/scholars, mentors and other appropriate faculty. Acceptable programs generally involve at least eight contact hours. A semester-long series of seminars/programs may be more effective than a single seminar or one-day workshop because it is expected that topics will then be considered in sufficient depth, learning will be better consolidated, and the subject matter will be synthesized within a broader conceptual framework.
        • Frequency of Instruction. Reflection on responsible conduct of research should recur throughout a scientist's career. Individual scholars are strongly encouraged to consider how to optimize instruction in responsible conduct of research for the particular career stage(s). Instruction must be undertaken at least once during each career stage, and at a frequency of no less than once every four years. Individuals at the early career investigator must receive instruction in responsible conduct of research at least once during this career stage.
    • Statement of research interests and career goals (limit to 1000 words)
    • Two mentor Support Letters
      • Outline the qualification of the applicant and the availability of resources for the applicant to complete their research
      • Additionally, mentors need to provide a statement regarding their role in career development of the ICTS-KL2 scholar. It should be stressed that primary review criteria include the extent of support provided by the mentor/department and the quality of mentoring.
    • A signed statement of support from the department chair or division chief.
      • This letter need only speak to the availability of resources for the applicant to perform research
    • NIH Biosketch (new format)


Notes and Deadlines

Full applications are due on Wednesday September 23 at 5pm.

Start date of funding: October 15, 2015

All application documents must be submitted online at www.icts.uci.edu/grants

All general questions should be directed to Diana Vigil dvigil1@uci.edu; (949)824-1231.

This award will follow all NIH Policies. The NIH Polices on K-awards can be found at http://grants.nih.gov/grants/policy/nihgps_2012/nihgps_ch12.htm